Behavioral sensitization (hyperactivity)

Record Type: Evaluation

Validation: GLP, Non-GLP

Models: Rat

Disease: CNS

Behavioral sensitization is the process by which repeat exposure to drugs of abuse can induce a progressively greater and enduring motor-stimulant response. 

Characterized by an increase in locomotor and/or stereotypic behavior, the effect can persist many months after the last drug administration, and mimics long-term sensitivity and drug abuse.

 

Regulatory

NDA & BLA

Industry Market

Pharma

Phase

Nonclinical